Table 1.
Participant Characteristics and Comparisons by Medication Condition
| Characteristic | Topiramate (n =
46) |
Placebo (n = 50)
|
t or χ2 | p |
|---|---|---|---|---|
| N (%) or M ± SD | N (%) or M ± SD | |||
| Age | 35.91 ± 12.04 | 35.74 ± 12.99 | −0.68 | .946 |
| Sex (female) | 18 (39.1) | 20 (40.0) | 0.00 | .931 |
| Race | 3.39 | .640 | ||
| White | 33 (71.7) | 36 (72.0) | ||
| African-American | 9 (19.6) | 10 (20.0) | ||
| American Indian | 1 (2.2) | 1 (2.0) | ||
| Asian/Pacific Islander | 2 (4.3) | 1 (2.0) | ||
| Mixed Race | 1 (2.2) | 2 (4.0) | ||
| Ethnicity (Hispanic)a | 5 (10.9) | 7 (14.3) | 0.25 | .616 |
| Cigarette smoker | 24 (52.2) | 23 (46.0) | 0.37 | .545 |
| Alcohol abuseb | 4 (8.7) | 5 (10.0) | 0.05 | .827 |
| Alcohol dependenceb | 19 (41.3) | 23 (46.0) | 0.22 | .643 |
| Drinks per drinking dayc | 6.60 ± 3.26 | 7.18 ± 5.62 | 0.61 | .543 |
| Drinking daysc | 73.23 ± 19.26 | 70.60 ± 21.70 | −0.63 | .533 |
| Heavy drinking daysc | 47.00 ± 27.76 | 45.16 ± 24.31 | −0.34 | .732 |
Note.
a
Ethnicity and race were not mutually exclusive;
b
Diagnostic status was identified in accordance with the Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition, Text Revision) using the Structured Clinical Interview for DSM-IV Axis I Disorders;
c
Derived from the 90-day Timeline Follow-Back interview conducted at baseline.