Table 1.
IVB | PRP | P value | |
---|---|---|---|
No of eyes (patients) | 22 (11) | 32 (17) | |
- Zone 1 | 16 (8) | 5 (3) | |
- Zone 2 | 6 (3) | 27 (14) | |
Mean birth age (weeks) | 24.2 ± 1.0 (23–26) | 24.8 ± 1.2 (23–28) | |
- Zone 1 | 24.3 ± 1.0 (23–26) | 24.4 ± 0.0 (24–24) | 0.70 |
- Zone 2 | 24.0 ± 1.0 (23–25) | 24.9 ± 1.3 (23–28) | 0.26 |
Mean birth weight (g) | 668.1 ± 127.3 (473–850) | 701.4 ± 118.8 (525–970) | |
- Zone 1 | 667.6 ± 117.4 (515–850) | 697.7 ± 89.6 (629–799) | 0.70 |
- Zone 2 | 669.3 ± 181.2 (473–830) | 702.2 ± 127.0 (525–970) | 0.71 |
Male sex (%) | 55% | 76% | 0.24 |
- Zone 1 | 63% | 100% | |
- Zone 2 | 33% | 71% | |
Mother's race (%) | 0.13 | ||
- Black | 45% | 41% | |
- White | 27% | 35% | |
- Hispanic | 0% | 23% | |
- Asian | 18% | 0% | |
- Other | 9% | 0% | |
Comorbidities (%) | 0.21 | ||
Intraventricular hemorrhage | 64% | 47% | |
- Grade I | 27% | 0% | |
- Grade II | 18% | 12% | |
- Grade III | 9% | 18% | |
- Grade IV | 1% | 18% | |
Necrotizing enterocolitis requiring surgery | 73% | 59% | |
Sepsis with positive cultures | 45% | 41% | |
Patent ductus arteriosus corrected with ligation | 18% | 18% | |
Mean Apgar score - 1 min | 3.1 ± 2.5 (1–8) | 3.8 ± 2.1 (1–7) | |
- Zone 1 | 3.5 ± 2.9 (1–8) | 5.0 ± 2.0 (3–7) | 0.43 |
- Zone 2 | 2.0 ± 1.0 (1–3) | 3.6 ± 2.1 (1–7) | 0.23 |
Mean Apgar score - 5 min | 5.8 ± 2.0 (2–8) | 6.3 ± 2.4 (1–9) | |
- Zone 1 | 6.3 ± 1.8 (4–8) | 7.3 ± 1.5 (6–9) | 0.37 |
- Zone 2 | 4.7 ± 2.5 (2–7) | 6.1 ± 2.6 (1–9) | 0.31 |
Mean age at treatment (PMA) | 35.1 ± 2.2 (31.7–38.0) | 36.1 ± 2.3 (32.7–39.9) | |
- Zone 1 | 34.9 ± 2.2 (31.7–38.0) | 33.6 ± 0.8 (32.7–34.1) | 0.76 |
- Zone 2 | 35.5 ± 2.7 (32.4–37.6) | 37.4 ± 2.0 (33.4–39.9) | 0.58 |
Follow-up period (months) | 21.7 ± 8.8 (9.8–33.7) | 34.5 ± 20.4 (6.8–72.8) | |
- Zone 1 | 19.1 ± 8.1 (9.8–33.7) | 38.6 ± 20.7 (14.9–52.8) | 0.04 |
- Zone 2 | 28.8 ± 7.5 (20.2–33.7) | 33.7 ± 21.0 (6.8–72.8) | 0.52 |
Data represent mean ± standard deviation (range) unless otherwise noted.