Skip to main content
. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Ophthalmology. 2015 Feb 14;122(5):1008–1015. doi: 10.1016/j.ophtha.2014.12.017

Table 1.

Characteristics of retinopathy of prematurity patients receiving intravitreal bevacizumab (IVB) or panretinal photocoagulation (PRP).*

IVB PRP P value
No of eyes (patients) 22 (11) 32 (17)
- Zone 1 16 (8) 5 (3)
- Zone 2 6 (3) 27 (14)
Mean birth age (weeks) 24.2 ± 1.0 (23–26) 24.8 ± 1.2 (23–28)
- Zone 1 24.3 ± 1.0 (23–26) 24.4 ± 0.0 (24–24) 0.70
- Zone 2 24.0 ± 1.0 (23–25) 24.9 ± 1.3 (23–28) 0.26
Mean birth weight (g) 668.1 ± 127.3 (473–850) 701.4 ± 118.8 (525–970)
- Zone 1 667.6 ± 117.4 (515–850) 697.7 ± 89.6 (629–799) 0.70
- Zone 2 669.3 ± 181.2 (473–830) 702.2 ± 127.0 (525–970) 0.71
Male sex (%) 55% 76% 0.24
- Zone 1 63% 100%
- Zone 2 33% 71%
Mother's race (%) 0.13
- Black 45% 41%
- White 27% 35%
- Hispanic 0% 23%
- Asian 18% 0%
- Other 9% 0%
Comorbidities (%) 0.21
  Intraventricular hemorrhage 64% 47%
  - Grade I 27% 0%
  - Grade II 18% 12%
  - Grade III 9% 18%
  - Grade IV 1% 18%
  Necrotizing enterocolitis requiring surgery 73% 59%
  Sepsis with positive cultures 45% 41%
  Patent ductus arteriosus corrected with ligation 18% 18%
Mean Apgar score - 1 min 3.1 ± 2.5 (1–8) 3.8 ± 2.1 (1–7)
- Zone 1 3.5 ± 2.9 (1–8) 5.0 ± 2.0 (3–7) 0.43
- Zone 2 2.0 ± 1.0 (1–3) 3.6 ± 2.1 (1–7) 0.23
Mean Apgar score - 5 min 5.8 ± 2.0 (2–8) 6.3 ± 2.4 (1–9)
- Zone 1 6.3 ± 1.8 (4–8) 7.3 ± 1.5 (6–9) 0.37
- Zone 2 4.7 ± 2.5 (2–7) 6.1 ± 2.6 (1–9) 0.31
Mean age at treatment (PMA) 35.1 ± 2.2 (31.7–38.0) 36.1 ± 2.3 (32.7–39.9)
- Zone 1 34.9 ± 2.2 (31.7–38.0) 33.6 ± 0.8 (32.7–34.1) 0.76
- Zone 2 35.5 ± 2.7 (32.4–37.6) 37.4 ± 2.0 (33.4–39.9) 0.58
Follow-up period (months) 21.7 ± 8.8 (9.8–33.7) 34.5 ± 20.4 (6.8–72.8)
- Zone 1 19.1 ± 8.1 (9.8–33.7) 38.6 ± 20.7 (14.9–52.8) 0.04
- Zone 2 28.8 ± 7.5 (20.2–33.7) 33.7 ± 21.0 (6.8–72.8) 0.52
*

Data represent mean ± standard deviation (range) unless otherwise noted.