Table 2.
Association between rest tremor and demographic and clinical variables
| Family Study of Essential Tremor (FASET) | Study of Environmental Epidemiology of ET | Essential Tremor Centralized Brain Repository (ETCBR) | |
|---|---|---|---|
| Age RT+ RT− |
72.1 ± 13.1 58.2 ± 17.7 t = 2.94, p =0.0041 |
74.3 ± 12.0 65.9 ± 15.5 t = 4.46, p <0.0011 |
85.0 ± 5.7 82.4 ± 5.6 t = 2.92, p = 0.0041 |
| Percent women RT+ RT− |
11 (73.3) 69 (48.6) X2 = 3.32, p=0.068 |
27 (48.2) 170 (52.5) X2 = 0.35, p = 0.56 |
51 (66,2) 50 (56.2) X2 = 1.75, p = 0.19 |
| Total tremor score RT+ RT− |
24.7 ± 6.8 19.7 ± 4.8 t = 3.66, p <0.0011 |
26.8 ± 7.7 22.4 ± 6.0 t = 4.06, p <0.0011 |
26.8 ± 7.7 22.4 ± 6.0 t = 4.06, p <0.0011 |
| Tremor duration RT+ RT− |
34.2 ± 19.8 32.3 ± 18.8 t = 0.38, p = 0.71 |
28.6 ± 22.0 21.9 ± 17.8 t = 2.54, p = 0.015 |
41.1 ± 21.8 39.9 ± 22.0 t = 0.34, p = 0.73 |
| Family history of ET RT+ RT− |
Not applicable (100% of cases had a family history of ET) |
18 (32.1) 98 (30.2) X2 = 0.08, p = 0.78 |
20 (26.0) 25 (28.1) X2 = 0.09, p = 0.76 |
| Family history of Parkinson’s disease RT+ RT− |
NA |
6 (10.7) RT−30 (9.3) RT−X2 = 0.12, p = 0.73 |
6 (7.8) RT−9 (10.1) RT−X2 = 0.27, p = 0.60 |
| Percent taking ET medication RT+ RT− |
10 (66.7) 69 (48.6) X2 = 1.77, p = 0.18 |
29 (51.8) 178 (54.9) X2 = 0.19, p = 0.66 |
51 (66.2) 58 (65.2) X2 = 0.02, p = 0.89 |
| Percent with voice tremor on examination RT+ RT− |
8 (53.3) 17 (12.0) X2 = 17.34, p <0.0011 |
23 (41.8) 92 (28.5) X2 = 3.95, p = 0.047 |
35 (45.5) 34 (38.2) X2 = 0.89, p = 0.34 |
| Percent with head tremor on examination RT+ RT− |
9 (60.0) 51 (35.9) X2 = 3.33, p = 0.068 |
27 (48.2) 115 (35.5) X2 = 3.42, p = 0.18 |
44 (57.1) 44 (49.4) X2 = 0.98, p = 0.32 |
| Percent with jaw tremor on examination RT+ RT− |
8 (50.0) 19 (13.2) X2 = 13.91, p<0.0011 |
14 (25.0) 27 (8.3) X2=13.78, p <0.0011 |
40 (54.1) 33 (34.4) X2 = 6.61, p = 0.01 |
All values are means ± standard deviations or proportions (percentages). RT+ = rest tremor present in either arm while seated or standing. RT− = rest tremor not present while seated or standing. NA = not assessed.
1
After Bonferroni correction, p < 0.05.