Table 2.

Baseline Demographic and Clinical Characteristics by Treatment Group

	Levodopa N=90		Placebo N=49
	N	%	N	%
Sex: Female	40	44%	24	49%
Race/Ethnicity
Asian	2	2%	1	2%
Black/African American	1	1%	1	2%
Hispanic or Latino	5	6%	2	4%
White	77	86%	44	90%
Unknown/not reported	5	6%	1	2%
Age at Randomization (Years)
7 to <9	39	43%	21	43%
9 to <11	33	37%	14	29%
11 to <13	18	20%	14	29%
Mean (SD) Years	9.4 (1.8)		9.5 (1.7)
Cause of Amblyopia
Strabismus	22	24%	5	10%
Anisometropia	20	22%	16	33%
Combined Mechanism	48	53%	28	57%
Patching Duration at Randomization
2 hours per day	81	90%	43	88%
≥ 3 hours per day	9	10%	6	12%
Visual Acuity in the Amblyopic Eye at Randomization
20/200 or worse (≤37 letters)	7	8%	9	18%
20/100 to <20/200 (38–52 letters)	34	38%	13	27%
20/80 (53–57 letters)	15	17%	8	16%
20/63 (58–62 letters)	20	22%	6	12%
20/50 (63–67 letters)	14	16%	13	27%
Mean (SD) letters	52.8 (9.8) ~20/80−2		51.7 (11.9) ~20/100+2
Visual Acuity in the Fellow Eye at Randomization
20/25 (78–82 letters)	15	17%	4	8%
20/20 (83–87 letters)	35	39%	20	41%
20/16 (88–92 letters)	34	38%	23	47%
20/12 (93–97 letters)	6	7%	2	4%
Mean (SD) letters	86.7 (4.1) ~20/20+2		87.3 (3.5) ~20/20+2
Intraocular Visual Acuity Difference at Randomization
Mean (SD) letters	33.9 (10.9) ~7 lines		35.6 (13.1) ~7 lines
SE Refractive Error in Ambylopic Eye at Randomization
Mean (SD) Diopters	+4.0 (2.6)		+4.5 (2.3)
SE Refractive Error in Fellow Eye at Randomization
Mean (SD) Diopters	+1.9 (2.0)		+1.6 (1.7)
Anisometropia at Randomization
Mean (SD) Diopters	+2.5 (2.1)		+3.1 (2.0)

SD = standard deviation; SE = spherical equivalent