Table 3.
Association Between Immune Mediated Conditions and Autism Spectrum Disorder (ASD) Stratified by Sex and Age Categories, Kaiser Permanente Northern California Members born 1980– 2003.
| sex | Age categories (years) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Immune condition | Male | Female | < 6 | 6 – 11 | 12 – 18 | 19 – 26 | ||||||
| Na | OR (95% CI) |
Na | OR (95% CI) |
Na | OR (95%CI) |
Na | OR (95% CI) |
Na | OR (95% CI) |
Na | OR (95% CI) |
|
| Asthma | 643 | 0.81 (0.74 – 0.89) |
117 | 0.96 (0.77 – 1.19) |
63 | 0.96 (0.71 – 1.28) |
227 | 0.85 (0.74 – 0.98) |
338 | 0.78 (0.69– 0.89) |
82 | 0.85 (0.65 – 1.09) |
| Any Allergies | 963 | 1.23 (1.14 – 1.34) |
185 | 1.16 (0.97 – 1.39) |
108 | 1.20 (0.95 – 1.51) |
403 | 1.16 (1.03 – 1.32) |
497 | 1.21 (1.08 – 1.36) |
140 | 1.52 (1.22 – 1.88) |
| Food allergy | 41 | 1.53 (1.08 – 2.18) |
8 | 2.22 (0.97 – 5.11) |
11 | 2.11 (1.03 – 4.29) |
24 | 2.22 (1.37 – 3.58) |
14 | 1.32 (0.73 – 2.38) |
0 | - |
| Rhinitis | 751 | 1.31 (1.12 – 1.40) |
137 | 1.28 (1.04 – 1.57) |
37 | 1.32 (0.90 – 1.92) |
291 | 1.24 (1.08 – 1.43) |
431 | 1.27 (1.12 – 1.43) |
129 | 1.53 (1.23 – 1.91) |
| Dermatitis | 319 | 1.04 (0.91 – 1.18) |
86 | 1.20 (0.93 – 1.54) |
79 | 1.06 (0.82 – 1.38) |
164 | 1.02 (0.85 – 1.21) |
137 | 1.13 (0.93 – 1.37) |
25 | 1.53 (0.97 – 2.42) |
| Other allergies | 437 | 1.26 (1.08 – 2.18) |
61 | 0.95 (0.71 – 1.26) |
36 | 1.26 (0.86 – 1.84) |
203 | 1.27 (1.08 – 1.50) |
217 | 1.15 (0.98 – 1.35) |
42 | 1.29 (0.90 – 1.83) |
| Any Autoimmune disorders | 50 | 1.49 (1.08 – 2.05) |
7 | 0.83 (0.37 – 1.86) |
2 | - | 11 | 0.91 (0.47 – 1.76) |
32 | 1.70 (1.13 – 2.57) |
12 | 1.19 (0.63 – 2.26) |
| Psoriasis | 18 | 2.88 (1.60 – 5.18) |
1 | - | 0 | - | 1 | - | 12 | 2.95 (1.42 – 6.10) |
6 | 3.61 (1.25 – 0.44) |
| Type 1 Diabetes | 10 | 1.14 (0.57 – 2.27) |
2 | - | 0 | - | 2 | - | 7 | 1.20 (0.52 – 2.78) |
3 | - |
a
Number of children with ASD