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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Brain Behav Immun. 2015 Feb 12;46:192–202. doi: 10.1016/j.bbi.2015.02.005

Fig. 7.

Fig. 7

Decreased Chrna7 in fetal brain led to the elevation of Il6 expression. (A) MIA increased Chrna7 mRNA level in wild-type fetal brain, but not in Chrna7+/− and Chrna7−/− fetal brain. (B) MIA increased Il6 mRNA in wild-type fetal brains but not in Chrna7+/− and Chrna7−/− fetal brains. Baseline Il6 levels were elevated in Chrna7+/− and Chrna7−/− fetal brains. Gene expression was normalized by β-actin.Saline +/+ n = 3 litters, +/− n = 3 litters, −/− n = 3 litters; Poly(I:C) +/+ n = 3 litters, +/− n = 3 litters, −/− n = 2 litters. Chrna7: nicotinic acetylcholine receptor alpha 7 subunit, Il6: interleukin-6. Data are presented as Mean ± SEM. Significant difference between groups is labeled as * p < 0.05, ** p < 0.01, **** p < 0.0001.