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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: J Pediatr. 2015 Mar 4;166(5):1168–1174.e2. doi: 10.1016/j.jpeds.2015.01.045

Table 1.

Patient and Visit Characteristics by Pattern of Hypertonic Saline Utilization in 42 PHIS Hospitals

Variables Non-Recipients (n=61498) Daily HTS (n= 1115) Trial HTS (n= 207) Rescue HTS (n= 326) Sporadic HTS (n=191) P-value
Age (months), mean (SD) 4.13 (3.40) 3.72 (3.14) 4.03 (3.35) 3.44 (3.14) 3.39 (3.11) <0.001
Male Sex, % 58.8 59.6 62.3 62.3 59.2 0.51
Race, %
 Black 22.1 12.6 25.1 18.1 15.2 0.05
 White 54.0 69.3 55.6 56.8 67.0
 Other 18.7 16.3 18.4 23.0 16.8
 Unknown 5.2 1.8 1.0 2.2 1.0
Asthma Diagnosis, % 6.6 7.0 10.1 8.3 6.3 0.45
Insurance Category, %
 Medicaid 60.5 66.5 60.9 58.6 73.3 0.32
 Private 24.6 28.1 29.5 28.8 20.9
 Self Pay 1.3 2.2 0.5 0.6 1.0
 Other 5.4 1.5 1.9 3.7 1.6
 Unknown 8.2 1.6 7.2 8.3 3.1
Season, %
 Summer (June–Aug) 3.5 1.8 2.9 3.1 4.2 0.46
 Fall (Sept–Nov) 13.7 9.1 11.6 14.4 4.7
 Winter (Dec–Feb) 60.2 59.4 63.3 58.0 60.7
 Spring (Mar–May) 22.6 29.8 22.2 24.5 30.4
Year, %
 2008 8.1 0.4 2.4 0.6 0.5 <0.001
 2009 30.0 5.4 15.0 16.9 11.0
 2010 31.2 26.4 25.6 34.7 26.7
 2011 30.7 67.8 57.0 47.9 61.8
Severity, %
 Intensive Care Unit Admission 7.2 3.9 21.7 30.7 38.2 <0.001
 Non-Invasive Positive Pressure Ventilation 2.3 0.7 9.2 13.5 11.5 0.004
 Mechanical Ventilation 1.0 0.0 1.9 0.9 3.7 *
 Blood Gas Measurement 14.1 15.7 34.8 43.3 51.3 <0.001
 Supplemental Oxygen 45.7 49.7 64.3 75.2 86.4 <0.001
 APR-DRG Severity Subclass (major/extreme) 7.6 6.6 19.8 24.5 29.8 <0.001
Management, %
 Racemic Epinephrine 16.9 41.9 48.8 51.2 61.3 0.002
 Albuterol 52.5 55.2 74.9 84.0 85.9 <0.001
 Corticosteroids 15.7 16.1 27.5 27.3 28.3 0.006
 Continuous Nebulized Therapies 5.5 13.3 22.2 25.8 33.0 0.002
 Intravenous Fluids 52.8 53.5 70.0 69.9 79.1 <0.001
 Intravenous Antibiotics 23.8 18.7 30.0 40.2 48.2 0.006
 Chest Radiographs 52.6 46.5 59.9 76.1 84.8 0.11
Length of Stay (days), mean (SD) 2.80 (2.52) 2.42 (1.78) 4.05 (2.63) 7.05 (3.47) 7.56 (3.33) <0.001
*

P-value not calculated due to empty cells