Table 2.

Mean hospital costs (2012 $) of patients with a primary diagnosis of ischemic stroke, by atrial fibrillation (AFib) status, 2010-2012 MarketScan Commercial Claims and Encounters Database Inpatient Admissions

	Total	Without AFib	With AFib	Mean Difference Between with AFib and without AFib (p-value)

Non-repeat Stroke Admissions¹	N=33,500	N=31,093	N=2,407
Total	19,138	18,779	23,770	4,991 (< 0.001)

Age (years)
18-54	19,710	19,469	24,908	5,439 (<0.001)
55-64	18,732	18,263	23,379	5,116 (<0.001)

Sex
Male	19,194	18,786	23,802	5,016 (<0.001)
Female	19,058	18,769	23,709	4,939 (<0.001)

Metropolitan Statistical Area
Yes	19,489	19,128	24,047	4,920 (<0.001)
No	17,531	17,199	22,332	5,133 (<0.001)

Region²
Northeast	19,757	19,341	23,841	4,500 (<0.001)
North Central	18,773	18,473	22,969	4,496 (<0.001)
South	17,962	17,685	22,133	4,448 (<0.001)
West	23,365	22,796	29,163	6,367 (<0.001)

Length of Stay (LOS)
<5 days	14,322	14,203	16,314	2,111 (<0.001)
≥5 days	31,798	31,558	33,704	2,147 (=0.014)

Repeat Stroke	N=6,582	N=6,185	N=397
Admissions

Total	21,126	20,929	24,199	3,269 (=0.002)

Age (years)
18-54	21,634	21,487	25,471	3,985 (=0.053)
55-64	20,741	20,487	23,741	3,254 (=0.007)

Sex
Male	21,228	20,850	26,582	5,732 (<0.001)
Female	20,992	21,033	20,273	−759 (=0.643)

Metropolitan Statistical Area
Yes	21,744	21,623	23,640	2,017 (=0.087)
No	18,270	17,716	26,719	9,003 (<0.001)

Region
Northeast	22,525	22,398	24,164	1,765 (=0.391)
North Central	20,785	20,546	24,383	3,837 (=0.041)
South	19,584	19,388	23,002	3,615 (=0.028)
West	26,037	25,842	29,444	3,602 (=0.439)

LOS
<5 days	13,912	13,899	14,157	259 (=0.727)
≥5 days	31,042	30,786	34,393	3,607 (=0.058)

An admission was a non-repeat stroke admission if it was the only admission for a patient during the study period of 2010-2012; otherwise, it was classified as a repeat stroke admission.

Northeast region includes Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island, Vermont, New Jersey, New York, and Pennsylvania; North Central region includes Illinois, Indiana, Michigan, Ohio, Wisconsin, Iowa, Kansas, Minnesota, Missouri, Nebraska, North Dakota, and South Dakota; South region includes are Washington D.C., Delaware, Florida, Georgia, Maryland, North Carolina, South Carolina, Virginia, West Virginia, Alabama, Kentucky, Mississippi, Tennessee, Arkansas, Louisiana, Oklahoma, and Texas; West region includes Arizona, Colorado, Idaho, Montana, Nevada, New Mexico, Utah, Wyoming, Alaska, California, Hawaii, Oregon, and Washington.