Table 2.
In-hospital mortality and odds ratio (unadjusted and adjusted) for hospital mortality, relative to normothermia (37–37.4 °C), for ANZ patients
| Peak temp (°C) | In-hospital mortality deaths, N (%) | Unadjusted odds ratio for in-hospital mortality (95 % CI)a | Adjusted odds ratio for in-hospital mortality (95 % CI)b |
|---|---|---|---|
| TBI/stroke (n = 38,679) | |||
| <36.0 | 505/1,139 (44.3) | 3.63 (3.20, 4.13) | 2.36 (1.98, 2.82) |
| 36.0–36.4 | 572/2,215 (25.8) | 1.59 (1.43, 1.77) | 1.62 (1.40, 1.87) |
| 36.5–36.9 | 1,117/6,273 (17.8) | 0.99 (0.91, 1.07) | 1.14 (1.03, 1.27) |
| 37.0–37.4 | 1,871/10,407 (18.0) | 1.00 | 1.00 |
| 37.5–37.9 | 9,074/1,797 (19.8) | 1.13 (1.05, 1.21) | 0.91 (0.83, 1.00) |
| 38.0–38.4 | 1,339/5,846 (22.9) | 1.36 (1.25, 1.47) | 0.93 (0.84, 1.02) |
| 38.5–38.9 | 698/2,477 (28.2) | 1.79 (1.62, 1.98) | 1.10 (0.97, 1.25) |
| 39.0–39.4 | 339/806 (42.1) | 3.31 (2.85, 3.84) | 1.62 (1.34, 1.96) |
| 39.5–39.9 | 142/262 (54.2) | 5.40 (4.21, 6.92) | 1.94 (1.40, 2.67) |
| 40.0+ | 131/180 (72.0) | 12.20 (8.75, 17.00) | 2.97 (1.95, 4.52) |
| CNS infection (n = 2,463) | |||
| <36.0 | 7/42 (16.7) | 1.86 (0.78, 4.43) | 2.15 (0.82, 5.62) |
| 36.0–36.4 | 14/100 (14.0) | 1.51 (0.79, 2.88) | 1.89 (0.88, 4.04) |
| 36.5–36.9 | 31/253 (12.3) | 1.30 (0.79, 2.12) | 1.78 (1.03, 3.08) |
| 37.0–37.4 | 43/442 (9.7) | 1.00 | 1.00 |
| 37.5–37.9 | 41/438 (9.4) | 0.96 (0.61, 1.50) | 1.15 (0.70, 1.91) |
| 38.0–38.4 | 52/444 (11.7) | 1.23 (0.80, 1.89) | 1.25 (0.78, 2.02) |
| 38.5–38.9 | 50/321 (15.6) | 1.71 (1.11, 2.65) | 1.36 (0.83, 2.22) |
| 39.0–39.4 | 32/247 (13.0) | 1.38 (0.85, 2.25) | 1.20 (0.70, 2.07) |
| 39.5–39.9 | 17/115 (14.8) | 1.61 (0.88, 2.94) | 1.30 (0.67, 2.55) |
| 40.0+ | 8/61 (13.1) | 1.40 (0.62, 3.14) | 1.08 (0.43, 2.72) |
Tests for interaction between TBI/stroke and CNS infection:
a P < 0.0001
b P = 0.02