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. 2010 Mar 17;102(6):401–409. doi: 10.1093/jnci/djq018

Table 2.

Baseline characteristics according to contralateral prophylactic mastectomy (CPM) status (N = 107 106) 1998–2003*

CPM not performed (n = 98 204)
CPM performed (n = 8902)
Characteristic No. % No. % χ2 statistic
Age, y
    18–49 (referent) 23 605 24 3731 42 2200
    50–59 22 251 23 2629 30
    60–90 52 348 53 2542 29
Race and/or ethnicity§
    Non-Hispanic white (referent) 72 408 74 7584 85 575.97
    Hispanic white 8211 8 469 5
    Black 8824 9 414 5
    Asian or Pacific Islander 8406 9 407 5
    Other unspecified or unknown 355 0 28 0
AJCC 5th cancer stage
    0 (referent) 12 833 13 1714 19 382.33
    I 31 523 32 3058 34
    IIA 24 805 25 2081 23
    IIB 18 157 18 1260 14
    IIIA 5900 6 468 5
    IIIB 4986 5 321 4
Lymph node status
    Negative (referent) 51 177 52 4802 54 160.70
    1–3 Positive 21 446 22 1863 21
    ≥4 Positive 15 198 15 1027 12
    Unknown 10 383 11 1210 14
Tumor grade
    I (referent) 12 879 13 1289 14 122.93
    II 36 032 37 3235 36
    III 34 601 35 2741 31
    IV 4031 4 474 5
    Unknown 10 661 11 1163 13
ER status
    Positive (referent) 56 043 57 4959 56 43.18
    Negative 17 689 18 1460 16
    Unknown or not done 24 472 25 2483 28
Histology type
    Nonlobular (referent) 79 835 81 6570 74 293.78
    Lobular 18 369 19 2332 26
First tumor diagnosis
    No (referent) 25 789 26 2882 32 155.64
    Yes 72 415 74 6020 68
*

Stage according to the American Joint Committee on Cancer (AJCC) Cancer Staging Manual, 5th edition. ER = estrogen receptor.

All P values were less than .001. P values were calculated using the χ2 statistic. All statistical tests were two-sided.

Median (interquartile range) age of diagnosis for CPM performed was 52 (45–61) years and for CPM not performed was 61 (50–73) years.

§

Percent data shown represent data analysis down each column; corresponding percent values in the text represent analysis across each row.