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. 2015 Apr 26;17(4):348–357. doi: 10.1016/j.neo.2015.02.006

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© 2015 The Authors.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

C-LOH but not V-LOH correlates with quantitative genotyping. Peak height ratios were calculated from Sanger sequence chromatograms for tumor (n = 26) and normal (n = 10) DNA samples. SNP peak height ratios for tumor samples were normalized to the average peak height ratio for normal tissue DNA and are shown as a function of genotype array z-scores for those tumor samples. Top panel: Combined analysis of four different SNPs found in patterns of C-LOH. Bottom panel: Combined analysis of four different SNPs found in patterns of V-LOH.