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. 2015 May;305(3):327–338. doi: 10.1016/j.ijmm.2015.01.002

Table 2.

Third level FunCat Enrichment Analysis* of genes differentially expressed.

FunCat ID Category 15 min 30 min 1 h 3 h
Down hits (p-value) Up hits (p-value) Down hits (p-value) Up hits (p-value) Down hits (p-value) Up hits (p-value) Down hits (p-value) Up hits (p-value)
11.06.01 rRNA modification 2 (4.43 × 10−3) 2 (1.65 × 10−2)
20.01.21 RNA transport 3 (7.44 × 10−3) 3 (4.51 × 10−2)
14.13.04 Lysosomal and vacuolar protein degradation 2 (2.22 × 10−2) 3 (1.27 × 10−2)
01.03.16 Polynucleotide degradation 3 (2.70 × 10−2)
16.03.03 RNA binding 5 (3.40 × 10−2) 8 (2.67 × 10−2) 8 (3.26 × 10−3)
32.07.07 Oxygen and radical detoxification 3 (6.28 × 10−3)
12.04.03 Translation termination 1 (4.10 × 10−2)
30.01.11 Ligand-dependent nuclear receptors 1 (4.10 × 10−2)
16.21.08 Fe/S binding 5 (3.02 × 10−5) 5 (4.29 × 10−6)
02.11.05 Accessory proteins of electron transport and membrane-associated energy conservation 5 (2.45 × 10−4) 6 (2.97 × 10−6)
11.02.01 rRNA synthesis 5 (1.29 × 10−3) 5 (2.47 × 10−4)
02.13.03 Aerobic respiration 5 (3.54 × 10−3) 8 (1.24 × 10−5)
02.13.01 Anaerobic respiration 2 (4.64 × 10−3) 2 (5.34 × 10−3)
16.21.07 NAD/NADP binding 7 (7.91 × 10−3)
20.01.15 Electron transport 9 (1.25 × 10−2) 15 (8.57 × 10−6) 6 (4.76 × 10−2)
01.03.01 Purin nucleotide/nucleoside/nucleobase metabolism 5 (1.83 × 10−2)
01.20.01 Metabolism of primary metabolic sugar derivatives 2 (3.42 × 10−2)
16.21.05 FAD/FMN binding 4 (4.54 × 10−2) 5 (1.46 × 10−2)
11.04.03 mRNA processing (splicing, 5′-, 3′-end processing) 13 (4.56 × 10−4) 17 (3.67 × 10−4)
11.04.02 tRNA processing 4 (2.05 × 10−2) 7 (9.41 × 10−4) 3 (1.29 × 10−2)
01.03.04 Pyrimidine nucleotide/nucleoside/nucleobase metabolism 4 (4.19 × 10−2)
16.01.01 Receptor binding 2 (4.28 × 10−2)
10.01.03 DNA synthesis and replication 6 (4.72 × 10−2) 10 (6.14 × 10−3)
01.01.05 Metabolism of urea cycle, creatine and polyamines 4 (1.82 × 10−3)
34.01.01 Homeostasis of cations 8 (1.17 × 10−2)
20.01.01 Ion transport 8 (1.56 × 10−2)
01.20.36 Non-ribosomal peptide synthesis 2 (2.58 × 10−2)
02.45.15 Energy generation (e.g. ATP synthase) 2 (3.08 × 10−2)
16.03.01 DNA binding 1 (4.23 × 10−2) 22 (3.16 × 10−3)
01.01.11 Metabolism of the pyruvate family (alanine, isoleucine, leucine, valine) and D-alanine 3 (4.46 × 10−2)
10.01.05 DNA recombination and DNA repair 17 (2.18 × 10−3)
40.10.02 Apoptosis (type I programmed cell death) 10 (3.40 × 10−3)
01.05.02 Sugar, glucoside, polyol and carboxylate metabolism 1 (4.87 × 10−3)
11.06.02 tRNA modification 5 (6.32 × 10−3)
14.07.07 Modification by ubiquitin-related proteins 5 (6.94 × 10−3)
10.01.02 DNA topology 7 (7.87 × 10−3)
01.05.03 Polysaccharide metabolism 1 (2.25 × 10−2)
32.01.09 DNA damage response 8 (2.51 × 10−2)
10.03.04 Nuclear and chromosomal cycle 7 (3.21 × 10−2)
20.09.18 Cellular import 5 (4.21 × 10−2)
16.19.03 ATP binding 24 (4.40 × 10−2) 12 (3.04 × 10−3)
01.20.31 Metabolism of secondary products derived from L-lysine, L-arginine and L-histidine 2 (4.48 × 10−2)
14.13.01 Cytoplasmic and nuclear protein degradation 12 (4.60 × 10−2)
11.04.01 rRNA processing 6 (4.11 × 10−3)
01.01.09 Metabolism of the cysteine – aromatic group 5 (2.92 × 10−2)
01.20.15 Metabolism of derivatives of dehydroquinic acid, shikimic acid and chorismic acid 2 (4.25 × 10−2)
20.03.22 Transport ATPases 3 (4.74 × 10−2)
32.07.01 Detoxification involving cytochrome P450 3 (2.18 × 10−2)
34.11.01 Photoperception and response 2 (2.34 × 10−2)
01.25.09 Extracellular lignin degradation 1 (3.25 × 10−2)
01.25.03 Extracellular protein degradation 1 (4.05 × 10−2)
*

p-value cutoff for enrichment analysis 0.05