Table 4.
List of Aspergillus fumigatus genes commonly identified by our study and by previous studies.
| Locus | Protein name | Incubation with Platelets for* | Incubation with | |||||
|---|---|---|---|---|---|---|---|---|
| 15 min | 30 min | 1 h | 3 h | Neutrophilsa | IDCsb | EACsc | ||
| Afu1g02610 | rRNA processing protein | −0.66 | −1.1 | −0.19 | −0.02 | ↑ | ||
| Afu1g09570 | Hypothetical protein | −0.11 | 0.68 | 1.23 | 0.1 | ↑ | ||
| Afu1g13370 | Aflatoxin B1-aldehyde reductase GliO-like | 0.71 | 1.35 | 0.45 | 0.84 | ↑ | ||
| Afu1g14550 | Mn superoxide dismutase MnSOD | −0.41 | −0.97 | −1.96 | −0.31 | ↑ | ↑ | |
| Afu1g16550 | Dihydrouridine synthase family protein | −0.99 | −0.3 | 0.56 | −1.59 | ↑ | ||
| Afu2g02310 | Actin cortical patch protein Sur7 | −0.42 | −0.27 | −2.24 | 0.58 | ↑ | ||
| Afu2g03120 | Cell wall glucanase (Utr2) | −0.47 | −1.18 | −0.05 | −0.69 | ↑ | ||
| Afu2g07420 | Actin-bundling protein Sac6 | 0.21 | 0.54 | 2.28 | 0.88 | ↑ | ||
| Afu2g07500 | Prolidase pepP | −0.62 | −1.53 | −1.1 | 0.38 | ↑ | ||
| Afu2g10330 | Hypothetical protein | −0.3 | 2.42 | 2.8 | −0.15 | ↑ | ||
| Afu2g15960 | Nucleotide binding protein Nbp35 | 0.05 | 0.64 | 1.23 | 0.07 | ↑ | ||
| Afu2g16750 | Nonsense-mediated mRNA decay protein 3 | −0.58 | 0.56 | 1.63 | −0.87 | ↑ | ||
| Afu3g00810 | Cholestenol delta-isomerase | −1.1 | −0.75 | −0.46 | −0.48 | ↑ | ||
| Afu3g00850 | Hypothetical protein | −0.75 | −1.13 | −0.98 | −0.71 | ↑ | ||
| Afu3g01260 | Acetyltransferase, GNAT family family | 0 | 1.26 | 1.2 | −0.62 | ↓ | ||
| Afu3g01580 | GMC oxidoreductase | −0.09 | 3.9 | 3.3 | 0.03 | ↑ | ||
| Afu3g02270 | Mycelial catalase Cat1 | 3.41 | 0.17 | −0.31 | 3.41 | ↑ | ||
| Afu3g06070 | Histone H1 | −0.48 | −1.65 | −1.45 | 0.08 | ↑ | ||
| Afu3g07850 | Pheromone maturation dipeptidyl aminopeptidase DapB | −1.28 | −0.69 | −1.33 | -0.62 | ↑ | ||
| Afu3g07910 | UDP-glucose 4-epimerase | 0.76 | 0.49 | 0.21 | 1.11 | ↑ | ||
| Afu3g08110 | Cell wall protein | −0.32 | −0.84 | −1.63 | −0.07 | ↑ | ||
| Afu3g10770 | RTA1 domain protein | 0.14 | 1.68 | 1.86 | −1.03 | ↑ | ||
| Afu4g01140 | MFS multidrug transporter | 2.16 | 2.23 | 1.12 | 1.49 | ↓ | ||
| Afu4g05900 | Hypothetical protein | −0.36 | 0.42 | 1.14 | −0.64 | ↑ | ||
| Afu4g10410 | Aspartate aminotransferase | 0.38 | −0.12 | −0.17 | 1.14 | ↑ | ↑ | |
| Afu4g11130 | Hypothetical protein | 1.35 | 1.31 | 0.67 | 2.04 | ↑ | ||
| Afu4g14250 | Hypothetical protein | 1.1 | -0.08 | 0.3 | 2.29 | ↓ | ||
| Afu5g01740 | Deoxyhypusine synthase | −0.42 | −0.48 | −1.49 | −0.3 | ↑ | ||
| Afu5g02330 | Major allergen and cytotoxin AspF1 | −0.36 | −1.34 | −1.46 | −0.34 | ↓/↑ | ||
| Afu5g03560 | Glutamyl-tRNA synthetase | 0.36 | 0.58 | 1.33 | 0.75 | ↑ | ||
| Afu5g05830 | CorA family metal ion transporter | −0.83 | −0.65 | −1.2 | −0.7 | ↑ | ||
| Afu6g03680 | Hypothetical protein | 1.5 | 0.69 | 0.2 | 3.68 | ↑ | ||
| Afu6g13150 | Hypothetical protein | 0.84 | 1.32 | 0.22 | 0.85 | ↑ | ||
| Afu6g14090 | CFEM domain protein | −0.32 | −2.33 | −2.85 | −0.01 | ↑ | ||
| Afu7g00580 | Hypothetical protein | 1.54 | −0.31 | 0.9 | 2.1 | ↑ | ||
| Afu7g03830 | DNA repair protein Rad7, protein | 0.52 | 1.99 | 2.31 | 0.53 | ↑ | ||
| Afu7g04290 | Amino acid permease (Gap1) | 1.44 | 0.6 | −0.39 | 1.57 | ↑ | ↑ | |
| Afu8g05710 | MFS sugar transporter Stl1 | 1.35 | 3.73 | 3.25 | −0.09 | ↑ | ↑ | |
| Afu8g07130 | AhpC/TSA family thioredoxin peroxidase | 0.16 | -2.02 | −2.59 | 0.27 | ↑ | ↑ | |
*
Log 2 relative fold change.
a
Sugui et al.
b
Immature dentritic cells, Morton et al.
c
Epithelial airway cells, Oosthuizen et al.; ↑…up-regulation; ↓…down-regulation.