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. Author manuscript; available in PMC: 2015 Apr 30.
Published in final edited form as: Biomed Microdevices. 2014 Aug;16(4):609–615. doi: 10.1007/s10544-014-9863-3

Fig. 3.

Fig. 3

Cancer spheroid formation in the microcavity wells and spheroid size control. a MDA-MB-231 breast cancer spheroid formation process from initial cell seeding to spheroid formation; scale bar: 200 μm. b The diameter of cell area in the lateral direction over 16 h. Statistics: 1-way ANOVA; n.s.: not significant. Error bars: SD. c Multicellular spheroids of MDA-MB-231 cells with different diameters were formed by controlling areal seeding density of cells on a microcavity substrate replicated from 500 μm beads, and quantification of spheroid diameter in relation to the seeding density. Error bars: SD. Scale bar: 100 μm