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TASK-1 inhibition increases α-cell electrical excitability. A and B, Representative mouse α-cell electrical activity in response to 14mM glucose alone (gray bar) and 14mM glucose with 250nM A1899 (black bar). C, Human α-cell electrical activity recorded in the presence of high glucose alone (14mM, gray bar) or with 250nM A1899 (black bar).
