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. 2015 Mar 31;19(1):132. doi: 10.1186/s13054-015-0831-y

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© Ristagno et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Association of plasma copeptin and free cortisol values at the time of admission and 48 hours later with 12-month outcomes. Copeptin levels changed over time in both groups (P <0.001), with no interaction between outcome and time (P = 0.847). There was no significant change over time (P = 0.313) and no interaction between time, patient outcomes (P = 0.221), and cortisol levels.