Table 4.
fabI / gyrA ratio of laboratory and clinical strains
| Strains | Log 2 fabI/gyrA ratio* |
t
test vs
parental strain |
t test vs ATCC 6538 | t test vs ATCC25923 |
|---|---|---|---|---|
| Laboratory strains | ||||
| RN4220 (n = 6) | 1.69 | |||
| MO034 (n = 5) | 2.49 | 0.04 | ||
| MO035 (n = 5) | 3.37 | 0.0002 | ||
| MO036 (n = 3) | 1.41 | ns | ||
| MU50 (n = 5) | −0.28 | |||
| ATCC6538 (n = 4) | 0.14 | |||
| MO052 (n = 4) | 2.14 | 0.0002 | ||
| ATCC25923 (n = 4) | −0.51 | |||
| Clinical strains | ||||
| QBR-102278-1052 (n = 4) | 4.22 | <0.0001 | <0.0001 | |
| QBR-102278-1889 (n = 4) | 1.25 | 0.0026 | 0.0137 | |
| QBR-102278-1969 (n = 4) | 1.56 | 0.0002 | 0.0059 | |
| QBR-102278-2363 (n = 4) | 1.16 | 0.004 | 0.016 | |
| QBR-102278-1016 (n = 3) | 0.23 | ns | ns | |
| QBR-102278-1027 (n = 4) | 0.13 | ns | ns | |
| QBR-102278-2628 (n = 5) | 0.03 | ns | ns |
*Log2 ratio was independently determined for each chip using the data before stage-wise quantile normalization, by subtracting the Log2 mean gyrA values obtained from the eight probes for gyrA printed on the chip from the Log2 mean fabI values from the two probes. Ratio was then further averaged for the number of chips used by strains (n). Student’s unpaired t-test was performed by comparing the mutants to their parental strains in the case of laboratory strains, or to two reference strains in the case of clinical isolates. ns = not significant.