Table 3.
Relative risks (RR) and 95% confidence intervals (CI) for prostate cancer risk according to quartiles of estimated phytanic acid intake in the ATBC Study, 1985–2006.
| Quartiles of estimated phytanic acid intake
|
p trend | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | ||
| All prostate cancer cases (no.) | 474 | 477 | 475 | 503 | |
| Age- and energy-adjusted1 RR (95% CI) | 1.0 | 0.99 (0.87–1.12) | 0.98 (0.86–1.11) | 1.05 (0.93–1.19) | 0.49 |
| Multivariate2 RR (95% CI) | 1.0 | 0.99 (0.87–1.12) | 0.97 (0.85–1.11) | 1.04 (0.91–1.20) | 0.68 |
| Localized prostate cancer cases (no.) | 211 | 180 | 175 | 215 | |
| Age- and energy-adjusted1 RR (95% CI) | 1.0 | 0.83 (0.68–1.01) | 0.78 (0.64–0.95) | 0.94 (0.78–1.14) | 0.44 |
| Multivariate2 RR (95% CI) | 1.0 | 0.83 (0.68–1.01) | 0.76 (0.62–0.94) | 0.91 (0.74–1.13) | 0.23 |
| Advanced prostate cancer cases (no.) | 86 | 126 | 114 | 112 | |
| Age- and energy-adjusted1 RR (95% CI) | 1.0 | 1.42 (1.08–1.87) | 1.26 (0.95–1.67) | 1.23 (0.93–1.63) | 0.28 |
| Multivariate2 RR (95% CI) | 1.0 | 1.43 (1.09–1.89) | 1.31 (0.99–1.75) | 1.38 (1.02–1.89) | 0.06 |
1
Energy adjustment performed using the residual methods
2
Further adjusted for smoking dose and duration, trial intervention assignment, education level, and dietary fat intake