Figure 1.

A portion of a transcriptional regulatory network inferred by the CARRIE web service from a microarray study (14) of the transcriptional response to alpha factor stimulation in S.cerevisiae and the KEGG (13) MAP kinase pathway description file. Solid black lines indicate the transcriptional regulation of a gene (in white) from the microarray experiment by a transcription factor (in red). Dashed black lines indicate the inferred indirect regulation of transcription factors by the initial stimulus receptor (in green). Blue nodes and arrows indicate additional information gained by including KEGG data. Blue labels indicate the nature of the interactions of the corresponding blue arrows as annotated by KEGG.