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. 2015 Apr 30;5:9818. doi: 10.1038/srep09818

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(A) AZA-1 at nanomolar concentrations did not produce an inhibition of I_Na in Nav 1.6 transfected cells. However a decrease of the current was observed when AZA-1 was added to pretreated cells with 1mM glutaric acid. (B) Histogram showing the inhibition of I_Na peak with the highest AZA-1 concentrations tested in presence of glutaric acid or glutarylcarnitine. (C) Representative current traces of I_Na in the presence of 100 nM AZA-1 alone or in combination with glutaric acid (pH 7.4).