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. 2015 Apr 30;5:9905. doi: 10.1038/srep09905

Table 2. Meta-analysis of the association between XRCC1-Arg 399 Gln polymorphism and prostatic cancer risk.

  AG vs. AA GG vs. AA Recessive model Dominant model
  OR(95%CI) P Phet I2(%) OR(95%CI) P Phet I2(%) OR(95%CI) P Phet I2(%) OR(95%CI) P Phet I2(%)
Overall 0.95(0.83,1.09) 0.480 0.043 41.3 1.24(1.00,1.53) 0.047 0.048 40.4 1.20(1.06,1.36) 0.005 0.100 32.8 1.07(0.92,1.26) 0.373 0.001 59.2
Ethnicity                                
Asian 1.03(0.70,1.52) 0.873 0.061 59.3 1.55(1.02,2.35) 0.039 0.388 0.8 1.43(1.02,2.00) 0.038 0.383 1.9 1.13(0.81,1.58) 0.468 0.110 50.3
Caucasian 0.98(0.80,1.19) 0.817 0.062 49.9 1.06(0.79,1.42) 0.720 0.058 50.7 1.05(0.89,1.23) 0.567 0.146 37.1 1.10(0.85,1.44) 0.466 0.000 76.4
Africa 0.82(0.65,1.03) 0.086 0.480 0.0 1.48(1.09,2.01) 0.012 0.779 0.0 1.64(1.23,2.18) 0.001 0.934 0.0 0.97(0.79,1.19) 0.774 0.433 0.0
Source of control                                
PB 0.95(0.78,1.15) 0.576 0.040 49.0 1.38(0.99,1.91) 0.056 0.011 58.1 1.22(1.05,1.43) 0.012 0.016 55.7 1.05(0.87,1.26) 0.647 0.019 54.5
HB 0.95(0.76,1.20) 0.692 0.165 36.2 1.07(0.84,1.37) 0.585 0.622 0.0 1.16(0.93,1.44) 0.196 0.869 0.0 1.12(0.86,1.46) 0.409 0.035 58.4

PB: population-based; HB: hospital-based.