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Defects of sporulation with the treatment of PrkA inhibitor ara-A. The strain Bacillus subtilis168 was cultured in 2x SG medium to induce sporulation. Sporulation frequencies of wild type (WT) strain without ara-A or with addition of ara-A were determined at 12, 24, and 36 h, respectively. The white histogram bar represents the WT strain, and the black bar represents ara-A-treatment group. ∗P < 0.01.
