TABLE II.
Demographic Characteristics and Presenting Symptoms of Children With Respiratory Syncytial Virus (RSV) or Seasonal Influenza and Sickle Cell Disease (SCD), Johns Hopkins Hospital 1993–2011
| Variable | RSV n = 64 | Influenza n = 91 |
P-Value |
|---|---|---|---|
| Age, years | 1.9 (1–3.5) | 4.8 (2, 11) | <0.0001 |
| Male | 50% | 62% | 0.16 |
| Genotype | 0.14 | ||
| HbSS | 75% | 86% | |
| HbSβ-thalassemia | 1.5% | 2% | |
| HbSC disease | 22% | 12% | |
| HbS-other | 1.5% | 0 | |
| Asthma | 23% | 28% | 0.51 |
| Chronic transfusion protocol | 2% | 18% | 0.002 |
| Wheezing | 22% (13/60) | 8% (7/84) | 0.03 |
| Retractions | 19% (10/54) | 6% (3/51) | 0.08 |
| Nasal Flaring | 8% (4/50) | 2% (1/50) | 0.36 |
| Grunting | 0 (0/43) | 2% (1/46) | 0.52 |