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. 2015 Apr 30;5:9851. doi: 10.1038/srep09851

Figure 1. Pulse generator, electrode, electric field simulation and typical waveform of pulses during treatment.

Figure 1

(a) Microsecond pulse generator was developed by State Key Laboratory of Power Transmission Equipment and System Security and New Technology, Chongqing University. Amplitude of output pulse voltage could reach up to 3 kV with the rise time at ns level, pulse width at μs level and the repetition rate of 1 ~ 100 Hz. The voltage amplitude and pulse width as well as repetition frequency is adjustable. (b) Two-needle electrode (10 mm-Tip, 0.5 mm diameter, variable gap from 1 mm to 20 mm) was bought from NEPA GENE Company, Japan. (c) Typical waveform of pulses during the application of μsPEFs. Pulses delivered to the tumors with the application of two-needle electrode, and DPO4054 real-time oscilloscope (Tektronix Company, U.S.) was used to monitor the waveform of pulses. (d) The electrode placement and electric field exposure simulation. The two white dots in the middle are the tips of needle electrode. The red area is full coverage overlapped by the electric field delivered by two electrodes. The scale showed the distance in mm.