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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Birth Defects Res A Clin Mol Teratol. 2015 Mar 16;103(4):276–283. doi: 10.1002/bdra.23362

Figure 2.

Figure 2

Quantile-quantile plots of expected versus observed −log10 p-values for the 13 CNP regions (A) and the corresponding 84 CNP components (B). The grey regions indicate confidence regions for the respective order statistics under an independence assumption, though the CNP components are highly correlated due to their proximity within regions.