Table 1.
Locations (hg18) and sizes of the two genomic regions on chromosomes 7q34 (upper row) and 8p11 (lower row) that showed the most significant over-transmission of the allele with the missing DNA segment from a hemizygous parent to an offspring, comparing trios with affected probands to control trios. These regions overlapped with the MGAM gene (chromosome 7), and ADAM3A / ADAM5 (chromosome 8), respectively.
chr | start | end | size | genes |
---|---|---|---|---|
7 | 141,380,317 | 141,447,476 | 67.2 kb | MGAM |
8 | 39,341,981 | 39,548,228 | 206.2 kb | ADAM3A, ADAM5 |