Table 1.
Representation of EtOH and water lever responses (means ± SEM) during the last 5 days of maintenance, the 1st day of extinction, and last 3 days extinction that were used for baseline prior to 1st PSR session.
| EtOH Lever (FR5) | Water Lever (FR1) | EtOH (g/kg) | |
|---|---|---|---|
|
|
|||
| Experiment 1 (SCH 23390 ; AcbShell) | |||
|
| |||
| EtOH Maintenance | 222 ± 22 | 13 ± 3 | 1.5 ± 0.2 |
| Extinction (Day 1) | 150 ± 13 | 12 ± 2 | |
| Base Extinction (last 3 days) | 32 ± 3 | 9 ± 1 | |
|
| |||
| Experiment 2 (SCH 23390 ; AcbCore) | |||
|
| |||
| EtOH Maintenance | 217 ± 21 | 12 ± 3 | 1.5 ± 0.2 |
| Extinction (Day 1) | 221 ± 22 | 17 ± 5 | |
| Base Extinction (last 3 days) | 22 ± 9 | 10 ± 2 | |
|
| |||
| Experiment 3 (A-77636; AcbShell) | |||
|
| |||
| EtOH Maintenance | 193 ± 15 | 10 ± 1 | 1.4 ± 0.3 |
| Extinction (Day 1) | 178 ± 15 | 15 ± 2 | |
| Base Extinction (last 3 days) | 32 ± 2 | 14 ± 3 | |
|
| |||
| Experiment 4 (A-77636; AcbCore) | |||
|
| |||
| EtOH Maintenance | 202 ± 22 | 10 ± 2 | 1.4 ± 0.2 |
| Extinction (Day 1) | 149 ± 14 | 24 ± 10 | |
| Base Extinction (last 3 days) | 30 ± 3 | 10 ± 1 | |
|
| |||