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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Med Res Rev. 2014 Aug 22;35(2):286–305. doi: 10.1002/med.21328

Figure 8.

Figure 8

Scheme of the active site of GABA-AT inactivated by vigabatrin (PDB 1OHW). Shown are the residues that interact with the new adduct. Rounded line indicates hydrophobic interaction. Dashed lines denote hydrogen bonds or salt bridges. Associated letters indicate the originating subunit.