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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Med Res Rev. 2014 Aug 22;35(2):286–305. doi: 10.1002/med.21328

Table I. Homologous residues in the active sites of OAT, GABA-AT and Asp-AT.

OATa GABA-ATb Asp-ATb
K292 K329 K258
R413 R445 R386
D263 D298 D222
S86 S73 -
R113 R100 -
F177 F189 W140
R180 R192 -
E235 E270 N194
E230 E265 H189
Q266 Q301 Y225
T322 T353 -
a

Adapted from Shen et al.4

b

Adapted from Toney et al.28