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Goodness-of-fit plots from the final PK model. (A) Identity plots of observed vs. population predicted TPM concentration. (B) Identity plot of observed vs. individual predicted TPM concentration. (C) Scatter plot of conditional weighted residuals (CWRES) vs. time. (D) Scatter plot of CWRES vs. population predicted TPM concentration. •, intravenous TPM; 
, oral TPM; 
, line of identity; 
, Loess, Smooth = 0.8
