Table 1.
Subject demographics for the ketoconazole and diltiazem DDI studies
| Characteristics | Ketoconazole (n = 20*) | Diltiazem (n = 18) | |
|---|---|---|---|
| Gender, n (%) | Male | 20 (100) | 13 (72) |
| Age (years) | Mean (SD) | 29 (6) | 29 (7) |
| Range | 21–45 | 22–45 | |
| Race, n (%) | White | 7 (35) | 7 (39) |
| Black | 10 (50) | 10 (56) | |
| Asian | 3 (15) | 1 (6) | |
| Body weight (kg) | Mean (SD) | 79 (11) | 78 (16) |
| Range | 64–107 | 53–109 | |
| BMI (kg m−2) | Mean (SD) | 25 (3) | 26 (3) |
| Range | 20–30 | 21–30 | |
*
Eighteen subjects completed the study: one subject discontinued the study due to an adverse event (rash) and one subject withdrew consent because of a family emergency. BMI, body mass index; DDI, drug–drug interaction; SD, standard deviation.