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. 2015 Apr 30;10(4):e0123807. doi: 10.1371/journal.pone.0123807

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© 2015 Japaridze et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 3 — A. Grand average of the sources described by DICS analysis during burst phase. The source of the strongest power in the frequency band 1–4 Hz was detected bilaterally in precuneus in all 13 patients. The 2nd source was detected bilaterally in the somatosensory cortex in all patients. The 3rd source was detected in prefrontal regions bilaterally; Subsequent sources were detected in the thalamus (4th source) bilaterally and the last coherent source was found in the brainstem, in all 13 patients. B. RPDC during burst phase: showing significantly (p = 0.003) stronger information flow from the precuneus (source 1) towards the somatosensory cortex (p = 0.001) (second source) and the prefrontal cortex (third source) (p = 0.004) as well as from the brainstem (source 5) towards the thalamus (p = 0.004) and from the thalamus to the precuneus (p = 0.004) rather than vice versa. Also, stronger RPDC (p = 0.002) was detected from the somatosensory cortex towards the prefrontal cortex.