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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Hepatology. 2014 Oct 2;60(5):1551–1562. doi: 10.1002/hep.27298

Fig. 3.

Fig. 3

Radar chart of HMAb neutralization patterns against the 16 HCVcc JFH1-based Core-NS2 recombinants of the genotype 1-3 panel. Only HMAbs exhibiting the most efficient neutralization ability, i.e. HC84.24, HC84.26, AR3A, AR4A, and HC-1AM are shown. Values in the radar chart display log10(IC50) values, with the maximum measured log(IC50) = 2. HCVcc with IC50 >100 μg/ml were defined as 3. Each data point represents an IC50-value against a specific virus isolate. The color code in the connecting lines represents the various included HMAbs. The selection of antibodies for cooperation analysis was based on minimizing the area towards the center of the graphs and the differences in epitope targets, thus suggesting that two given HMAbs would complement their respective IC50-values.