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. 2015 Apr 1;2(2):ENEURO.0029-14.2015. doi: 10.1523/ENEURO.0029-14.2015

Figure 5.

Figure 5

Synergized iLTD requires CB1R signaling. A, Group time course illustrating the lack of effect of 3× TBS-5 min BDNF combination on eIPSC amplitude in the presence of CB1R antagonist SR 141716A (SR, 10 μM, n = 6.) Inset, Averaged sample sweeps during baseline (1) and 35 min after TBS (2) from a representative experiment. B, Compiled group data for normalized eIPSC amplitude at 35 min post various induction conditions. Hatched light blue bar, 3× TBS. Hatched pink bar, 0.05 nM BDNF for 5 min. Purple bar, Combination of 5 min-0.05 nM BDNF and 3× TBS. Green bar, Combination of 5 min-0.05 nM BDNF and 3× TBS, in the presence of SR. Blue bar, 7tr-TBS (taken from Fig. 2C for comparison).