Figure 17.
Schematic representation of the nanoprecipitation process. (A) Injection of aqueous solution of alkyne functionalized polyglycerol macromonomers (red spheres), azide functionalized polyglycerol macromonomers (blue spheres) and the proteins asparaginase, IgG, Lysozyme and BSA (3D structure of α-helixes and β-turns). (B) Particle templation by diffusion of aqueous phase (blue arrow) into acetone phase (violet). (C) Particle gelation by azide alkyne 2+3 cycloaddition.
Reproduced with permission.[131] Copyright © 2013, Elsevier.