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. 2015 May;45(5):477–484. doi: 10.1016/j.ijantimicag.2015.01.009

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© 2015 Matthew J. Ellington

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 3 — Comparative and phylogenetic analyses of fused staphylococcal cassette chromosome (SCC) elements encoding both fusC and mecA. (A) SCC elements were formed from portions of SCCmec (in grey) and SCC₄₇₆-like cassettes (in teal) and were flanked by direct repeat sequences (DR_scc). Percentage DNA sequence homologies to the corresponding portion of SCCmecIVa or SCC₄₇₆ are shown above each SCCmec-fus. The change in sequence homology from SCCmec to SCC₄₇₆ (denoted and detailed by red numbers in red circles) occurred within coding sequences (shown as red arrow heads). (B) Four different SCCs were identified and were unique to ST1 in purple (SCC₄₇₆), ST5 in cyan and ST45 in orange. The reference cassettes SCC₄₇₆ and SCCfusC are shown in black.