Table 2.

Activation main effects of the n-back task in rMDD patients and HC (n = 120).

Region	BA	Cluster (mm3)	z	p	x	y	z
dlPFC	9, 45, 46	71,650	13.00	<0.001**	1	9	52
IPL	40	36,846	12.70	<0.001**	38	−46	41
amPFC	10	18,318	−11.96	<0.001**	−6	48	12
PCC	29, 30	6417	−12.26	<0.001**	−6	−52	21
MidSupITempG	21	1957	−10.53	<0.001**	−58	−8	−8
Insula	13	1591	−10.60	<0.001**	36	−19	21
vlPFC	24, 32, 33	1434	10.76	<0.001**	−16	−2	23
Insula	13	837	−10.36	<0.001**	−34	−19	21
PHG	28, 35	523	−9.55	<0.001**	−25	−22	−12
IMidFG	11, 47	241	−9.32	<0.001**	−38	31	−8

Positive z-scores indicate an increase and negative z-scores a decrease of activation; x, y, z are coordinates in Talairach space (LPI). Abbreviations: **, highly significant (FWE corrected p < 0.01); *, significant (FWE corrected p < 0.05); rMDD, remitted Major Depressive Disorder; HC, healthy controls; BA, Brodmann Area; FWE, family-wise error rate; dlPFC, dorsolateral prefrontal cortex; IPL, inferior parietal lobe; amPFC, anterior-medial prefrontal cortex; PCC, posterior cingulate cortex; MidSupITempG, middle, superior and inferior temporal gyrus; vlPFC, ventrolateral prefrontal cortex; PHG, parahippocampal gyrus; IMidFG, inferior and middle frontal gyrus.