Table 1. Urine and serum biochemistry.
Control | EG | EG+STS | EG+SC | EG+SS | ||
---|---|---|---|---|---|---|
Urine | Volume, ml/d T0 | 7.5 ± 2.0 | 7.2 ± 3.0 | 7.2 ± 2.6 | 8.6 ± 1.8 | 9.8 ± 2.8 |
Volume, ml/d T2 | 13.2 ± 3.6 | 25.6 ± 11.8 | 21.1 ± 6.9 | 19.4 ± 10.0 | 19.1 ± 9.6 | |
Volume, ml/d T4 | 17.2 ± 6.7 | 31.0 ± 5.9 | 26.4 ± 6.1 | 22.7 ± 9.9 | 23.4 ± 6.6 | |
Oxalate (μmol/d, T4) | 12.33 ± 1.64* | 93.72 ± 40.24 | 76.53 ± 37.13 | 53.63 ± 17.39 | 58.50 ± 30.98 | |
Calcium (mg/d, T4) | 3.55 ± 1.39* | 5.33 ± 0.96 | 4.98 ± 0.98 | 3.96 ± 1.42* | 4.45 ± 1.06 | |
Creatinine (mmol/d, T4) | 0.048 ± 0.01* | 0.037 ± 0.00 | 0.044 ± 0.00* | 0.038 ± 0.01 | 0.033 ± 0.00 | |
Serum | Calcium (mg/dl, T4) | 9.74 ± 1.19 | 9.72 ± 0.56 | 9.85 ± 1.25 | 9.00 ± 1.17 | 9.32 ± 1.24 |
Creatinine (μM, T4) | 50.73 ± 8.4* | 63.03± 11.0 | 50.84 ± 8.2* | 61.50± 14.8 | 57.23 ± 23 | |
CrCl (ml/min, T4) | 0.67 ± 0.20* | 0.44 ± 0.10 | 0.63 ± 0.19* | 0.46 ± 0.22 | 0.48 ± 0.22 |
Data are means ± SD from 7–8 animals per group. Significance levels are with reference to the EG group.
*p< 0.05 is statistically significant. T0 = week 0, T2 = week 2, T4 = week 4.