Table 4.
Factors associated with adherence to PrEP for combined daily and strict intermittent dosing groups
| Factor | Univariable analysis | Multivariable analysis | ||
|---|---|---|---|---|
| Estimate | p value | Estimate | p value | |
| Age (per year) | 0.7 | 0.35 | – | – |
| Years of education | 0.8 | 0.41 | – | – |
| Source of income | 0.04 | 0.03 | ||
| Self | 20.1 | 0.02 | 19.0 | 0.01 |
| Family | 22.6 | 0.03 | 18.8 | 0.04 |
| No employment | Reference | N/A | Reference | N/A |
| Financial Care of Dependents | −8.2 | 0.30 | – | – |
| Engaged in sex work in month prior to enrollment | −6.3 | 0.35 | – | – |
| Had sex with men in month prior to enrollment | −1.8 | 0.84 | – | – |
| Any sexa | −8.9 | 0.19 | – | – |
| # Sexual partnersa | 0.7 | 0.17 | – | – |
| Any occurrence of sex while drunka | −8.8 | 0.03 | – | – |
| Sex with a new partnera | 5.9 | 0.09 | 6.1 | 0.08 |
| <100 % condom use with new or HIV + partnersa | 1.4 | 0.74 | – | – |
| Involved in transactional sexa | −7.2 | 0.10 | −10.2 | 0.02 |
| Receptive anal intercoursea | −5.3 | 0.25 | – | – |
| Insertive anal intercoursea | 7.2 | 0.10 | – | – |
| <100 % condom use with anal intercoursea | −2.2 | 0.64 | – | – |
| Frequent travela | −7.4 | 0.02 | −5.1 | 0.09 |
| Any alcohol usea | −3.3 | 0.41 | – | – |
| Any drug usea | −4.4 | 0.41 | – | – |
| Duration on study (per study month)a | −4.6 | 0.0003 | −3.2 | 0.02 |
| Daily Dosing Regimenb | 25.9 | <0.0001 | 26.7 | <0.0001 |
Estimates should be interpreted as percentage point changes from the reference factor
aTime-varying covariate (measured monthly)
bDaily dosing regimen was retained in the multivariate model due to a priori interest