Table 1. Characteristics of the 291 patients with locally recurrent NPC.
| Patient characteristics | No. of patients (%) |
|---|---|
| Age (years) | |
| Median | 46 |
| Range | 21–79 |
| Gender | |
| Male | 225 (77.3) |
| Female | 66 (22.7) |
| Initial treatment | |
| Radiotherapy alone | 205(70.4) |
| CCRT±neoadjuvant/adjuvant chemotherapy | 75(25.8) |
| Radiotherapy+ neoadjuvant/adjuvant chemotherapy | 11(37.8) |
| Initial radiotherapy mode | |
| 2D-RT | 265(91.1) |
| 3D-CRT | 10(3.4) |
| IMRT | 7(2.4) |
| 2D-RT+brachetherapy | 8(2.7) |
| 3D-CRT+brachetherapy | 1(0.3) |
| Initial radiotherapy dose | |
| ≤70Gy | 179(61.5) |
| >70Gy | 112(38.5) |
| Recurrence interval (months) | |
| Median | 26 |
| Range | 6–265 |
| Histology | |
| WHO type I | 9 (3.1) |
| WHO type II-III | 232 (79.7) |
| Imaging findings only | 50 (17.2) |
| Recurrent T classification* | |
| rT1 | 20 (6.9) |
| rT2 | 27 (9.3) |
| rT3 | 117 (40.2) |
| rT4 | 127 (43.6) |
| Recurrent N classification* | |
| rN0 | 238 (81.8) |
| rN1 | 43 (14.8) |
| rN2 | 6 (2.1) |
| rN3 | 4 (1.4) |
| Recurrent clinical stage* | |
| rI | 15 (5.2) |
| rII | 30 (10.3) |
| rIII | 113 (38.8) |
| rIVA-B | 133 (45.7) |
| Salvage treatment | |
| Salvage IMRT alone | 45 (15.5) |
| Salvage IMRT + chemotherapy | 246 (84.5) |
Abbreviations: CCRT, concurrent chemoradiotherapy
* According to the 7th AJCC/UICC staging system.