Table A1.
Comparison of mouse strains: their dominant responses, antibodies involved for testing and list of experiments.
Mouse strain | Basic description | Biological elements | Experiments |
---|---|---|---|
BALB/c | Anti-inflammatory response dominates | Th2, Treg dominate (Treg treated with: anti-CD25 antibodies) | 1,4 |
C57BL/6 | Pro-inflammatory response dominates | Th17, Th1 dominate (treated with: anit-IL-6, anti-IL-12p40 antibodies) | 2,5–8 |
STAT6 KO BALB/c | BALB/c mice with Th2 response removed | Treg dominates | 3 |
Note: the Th2 response has both pro- and anti-inflammatory characteristics