Table 6.
Comparison of outcome measures between patients with ICU-AW and clinically strong patients
| Characteristic | Randomized cohort (ICU-AW) (n = 16) | Observational cohort (MRC-SS ≥ 48/60) (n = 14) | P |
|---|---|---|---|
| ISWT (m) | |||
| Baseline | 40 (10.0 to 80.0) | 80.0 (30.0 to 212.5) | 0.1 |
| Completion | 200.0 (120.0 to 330.0) | 365.0 (250.0 to 477.5) | 0.03 |
| Change | 120.0 (10.0 to 230.0) | 265.0 (207.5 to 300.0) | 0.047 |
| 6MWT (m) | |||
| Baseline | 160.0 (110.5 to 221.0) | 167.0 (60.0 to 293.5) | 0.8 |
| Completion | 330.0 (240.0 to 422.5) | 433.5 (318.3 to 481.0) | 0.1 |
| Change | 160.0 (36.5 to 208.5) | 157.5 (131.3 to 321.3) | 0.5 |
| SF-36 PCS (/100) | |||
| Baseline | 29.4 (19.7 to 32.9) | 34.0 (28.2 to 41.4) | 0.03 |
| Completion | 34.6 (46.5 to 55.1) | 42.7 (35.7 to 48.5) | 0.2 |
| Change | 6.3 (− 3.2 to 16.2) | 6.4 (1.7 to 13.1) | 0.9 |
| SF-36 PF (/100) | |||
| Baseline | 12.5 (5.0 to 27.5) | 40.0 (15.0 to 66.3) | 0.005 |
| Completion | 40.0 (20.0 to 73.8) | 70.0 (41.8 to 80.0) | 0.1 |
| Change | 20.0 (0.0 to 60.0) | 23.5 (3.8 to 31.3) | 0.8 |
| Barthel (/100) | |||
| Baseline | 87.5 (75.0 to 95.0) | 97.5 (85.0 to 100.0) | 0.08 |
| Completion | 100.0 (86.3 to 100.0) | 100.0 (98.8 to 100.0) | 0.5 |
| Change | 10.0 (1.3 to 23.8) | 0.0 (0.0 to 15.0) | 0.2 |
| TUAG (s) | |||
| Baseline | 21.0 (16.0 to 36.0) | 14.8 (13.1 to 18.5) | 0.04 |
| Completion | 10.0 (8.0 to 19.0) | 8.0 (6.8 to 10.0) | 0.06 |
| Change | − 7.0 (−24.0 to −2.0) | − 6.0 (− 9.3 to − 3.8) | 0.6 |
| STS-5 (s) | |||
| Baseline | 22.5 (16.8 to 29.5) | 19.0 (10.8 to 26.0) | 0.3 |
| Completion | 16.0 (11.5 to 20.0) | 11.4 (8.9 to 17.5) | 0.2 |
| Change | − 3.8 (− 15.0 to 1.9) | − 3.5 (− 11.0 to − 0.5) | 0.98 |
Data are presented as median (IQR). P values derived from Mann-Whitney test analysis. n = 14 for TUAG and STS-5 for the randomized cohort. SF-36 v2 PF indicates Short Form-36 v2 Physical Function domain; TUAG, Timed Up and Go; STS-5, Sit to Stand 5 times.