Table 2.
Age- and multivariable* adjusted hazard ratios (95% confidence intervals) of brain tumor according to headache status in the Women’s Health Study (N = 39,534)
| No headache (n = 26,512) | Any headache (n = 13,022) | Non-migraine headache (n = 5,731) | Any migraine (n = 7,291) | |||||
|---|---|---|---|---|---|---|---|---|
| No. of cases | Hazard ratio (95% CI) | No. of cases | Hazard ratio (95% CI) | No. of cases | Hazard ratio (95% CI) | No. of cases | Hazard ratio (95% CI) | |
| Age-adjusted | 32 | 1.00 (ref) | 20 | 1.35 (0.77, 2.37) | 10 | 1.53 (0.75, 3.13) | 10 | 1.21 (0.59, 2.47) |
| Multivariable adjusted* | 32 | 1.00 (ref) | 20 | 1.33 (0.76, 2.34) | 10 | 1.53 (0.75, 3.12) | 10 | 1.18 (0.58, 2.41) |
*Adjusted for age, body mass index (BMI) (<25, 25–29.9, ≥30 kg/m2), alcohol consumption (rarely/never, 1–3 drinks/months, 1–6 drinks/week, ≥1 drink/day), smoking status (never, past, current), postmenopausal status (premenopausal, postmenopausal, uncertain), and exercise (rarely/never, <1 time/week, 1–3 times/week, ≥4 times/week).