Table 3.
Multivariable* adjusted hazard ratios (95% confidence intervals) of brain tumor stratified by age according to headache status in the Women’s Health Study (N = 39,534)
| No headache (n = 26,512) | Any headache (n = 13,022) | Non-migraine headache (n = 5,731) | Any migraine (n = 7,291) | |||||
|---|---|---|---|---|---|---|---|---|
| No. of cases | Hazard ratio* (95% CI) | No. of cases | Hazard ratio* (95% CI) | No. of cases | Hazard ratio* (95% CI) | No. of cases | Hazard ratio* (95% CI) | |
| <55 years of age at baseline (N = 23,849) | 13 | 1.00 (ref) | 12 | 1.57 (0.72, 3.46) | 6 | 1.79 (0.68, 4.72) | 6 | 1.40 (0.53, 3.69) |
| ≥55 years of age at baseline (N = 15,685) | 19 | 1.00 (ref) | 8 | 1.10 (0.48, 2.53) | 4 | 1.28 (0.43, 3.78) | 4 | 0.96 (0.33, 2.85) |
*Adjusted for age, body mass index (BMI) (<25, 25–29.9, ≥30 kg/m2), alcohol consumption (rarely/never, 1–3 drinks/months, 1–6 drinks/week, ≥1 drink/day), smoking status (never, past, current), postmenopausal status (premenopausal, postmenopausal, uncertain), and exercise (rarely/never, <1 time/week, 1–3 times/week, ≥4 times/week).