Table 2.
Single nucleotide polymorphisms identified in the ADRB2 gene of subjects with asthma.
| Location | Nucleotide | SNPs | Allele frequency Caucasian Americans | Allele frequency African Americans | ||
|---|---|---|---|---|---|---|
| 5′‐flanking | −2,633 | C/T | 0.47 | 0.53 | 0.62 | 0.38 |
| −2,547 | G/T | 0.99 | 0.01 | 1.00 | 0.00 | |
| −2,387 | C/T | 0.51 | 0.49 | 0.40 | 0.60 | |
| −2,274 | C/T | 0.53 | 0.47 | 0.40 | 0.60 | |
| −2,047 | T/C | 1.00 | 0.00 | 0.98 | 0.02 | |
| −1,818 | A/T | 0.70 | 0.30 | 0.66 | 0.34 | |
| −1,531 | C/T | 0.81 | 0.19 | 0.78 | 0.22 | |
| −1,429 | T/A | 0.78 | 0.22 | 0.72 | 0.28 | |
| −1,343 | A/G | 0.51 | 0.49 | 0.38 | 0.62 | |
| −1,283 | G/T | 1.00 | 0.00 | 0.98 | 0.02 | |
| −1,261 | A/G | 0.99 | 0.01 | 1.00 | 0.00 | |
| −1,023 | A/G | 0.50 | 0.50 | 0.39 | 0.61 | |
| −722 | C/T | 0.98 | 0.02 | 1.00 | 0.00 | |
| −654 | G/A | 0.74 | 0.26 | 0.73 | 0.27 | |
| −468 | C/G | 0.46 | 0.54 | 0.72 | 0.28 | |
| −406 | C/T | 1.00 | 0.00 | 0.95 | 0.05 | |
| −367 | C/T | 0.49 | 0.51 | 0.20 | 0.80 | |
| −262 | G/A | 1.00 | 0.00 | 0.90 | 0.10 | |
| 5′‐UTR | −75 | G/A | 1.00 | 0.00 | 0.97 | 0.03 |
| −47 | C/T | 0.50 | 0.50 | 0.23 | 0.77 | |
| −20 | C/T | 0.51 | 0.49 | 0.25 | 0.75 | |
| Coding block | 46 | G/A | 0.73 | 0.27 | 0.52 | 0.48 |
| 66 | C/T | 0.99 | 0.01 | 0.97 | 0.03 | |
| 79 | G/C | 0.50 | 0.50 | 0.23 | 0.77 | |
| 252 | G/A | 0.80 | 0.20 | 0.78 | 0.22 | |
| 523 | C/A | 0.87 | 0.13 | 0.72 | 0.28 | |
| 1,053 | G/C | 0.82 | 0.18 | 0.71 | 0.29 | |
| 1,237 | G/A | 0.72 | 0.28 | 0.59 | 0.41 | |
| 3′‐UTR | 1,268 | C/G | 1.00 | 0.00 | 0.92 | 0.08 |
| 1,537 | T/C | 1.00 | 0.00 | 0.98 | 0.02 | |
| 1,626 | C/T | 0.99 | 0.01 | 1.00 | 0.00 | |