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. Author manuscript; available in PMC: 2016 Jan 27.
Published in final edited form as: Sci Signal. 2015 Jan 27;8(361):ra9. doi: 10.1126/scisignal.2005607

Table 1. FADD interacts with proteins involved in the G2/M transition.

The top cell cycle- related proteins that were pulled down with Halo-tagged FADD in HEK 293T cells. The cut off that determined FADD-interacting proteins was a spectral count (SpC) of 5 or greater and a control SpC of 0. NSAF is the normalized spectral abundance factor.

Identified Proteins Gene Symbol Molecular Weight (kD) FADD peptide SpC Control peptide SpC FADD NSAF Control NSAF

FADD FADD 23 555 0 0.104876887 0
CK1α CSNK1A1 39 20 0 0.002228846 0
Polo-Like Kinase 1 PLK1 68 5 0 0.000319577 0
Aurora Kinase B AURKB 39 6 0 0.000668654 0
Cell Division Cycle 20 CDC20 55 17 0 0.001343386 0
Centrosomal Protein 170 CEP170 175 11 0 0.000273193 0
Structural Maintence of Chromosomes 1A SMC1A 143 13 0 0.000395114 0
Non-SMC condensing II complex, subunit D3 NCAPD3 169 19 0 0.000166099 0
Non-SMC condensing II complex, subunit G2 NCAPG2 131 18 0 0.000597195 0
Non-SMC condensing II complex, subunit D2 NCAPD2 157 6 0 0.000166099 0
Dynactin 2 DCTN2 44 5 0 0.000493892 0
Cell Division Cycle 73 CDC73 61 7 0 0.0004875 0
Fanconi anemia complementation group D2 FANCD2 165 15 0 0.000392733 0
Fanconi anemia complementation group I FANCI 149 36 0 0.001050101 0
Cytoskeleton associated protein 5 CKAP5 226 7 0 0.000134618 0