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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Amino Acids. 2011 Aug 4;42(0):507–518. doi: 10.1007/s00726-011-1023-y

Fig. 2.

Fig. 2

Measurement of cardiac function in mice treated with ISO alone or L-Arg/ISO.

Ejection fraction (A.), shortening fraction (B.) and cardiac output (C.) were measured in mice drinking either water or 5% L-Arg and treated for two days with ISO. ISO NTG (n = 5), ISO TG (n = 5) and L-Arg/ISO NTG (n = 7) all show normal heart function. L-Arg/ISO TG (n = 7) showed significantly impaired systolic function, as measured by EF and SF. * statistically significant compared to NTG + L-Arg/ISO, P < 0.01; ** statistically significant compared to NTG + L-Arg/ISO, P < 0.002.