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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Arthritis Rheum. 2011 Nov;63(11):3253–3262. doi: 10.1002/art.30583

Figure 1.

Figure 1

Up-regulation of interferon regulatory factor 1 (IRF-1) in rheumatoid arthritis synovial fibroblasts (RASFs) exposed to tumor necrosis factor α (TNFα). RASFs (2 × 105/well; 2 ml/well) were stimulated with TNFα in serum-free media for 0–48 hours. IRF-1 expression was assessed at the mRNA level (A) and at the protein level (B). Bars show the mean ± SEM. * = P < 0.05. NS = nonstimulated. n = number of donors and independent experiments.