Table 3.
Effects of AELS, AEAR and aspirin on acetic acid induced writhing method
| Group | Treatment | Dose [mg/kg] | No. of writhes [15 min] (Mean ± S.E.M) | Inhibition (%) |
|---|---|---|---|---|
| I | Control | --- | 48.33 ± 1.13 | --- |
| II | Standard | 50 | 14.87 ± 0.09*** | 69.23% |
| III | AELS | 100 | 25.1 ± 0.12* | 48.05% |
| IV | AELS | 200 | 21.57 ± 0.11** | 55.36% |
| V | AELS | 400 | 17.83 ± 0.1*** | 63.10% |
| VI | AEAR | 100 | 28.63 ± 0.14 | 40.76% |
| VII | AEAR | 200 | 25.20 ± 0.13* | 47.86% |
| VIII | AEAR | 400 | 20.73 ± 0.10** | 57.10% |
Values are expressed as mean ± S.E.M (n = 6). *P < 0.05 (significant), **P < 0.01 (more significant) and ***P < 0.001 (most significant) compared with vehicle control (ANOVA followed by Dunnet’s t-test).