Table 2.
KEGG pathway analysis for the predicted miRNA targets related with EV71 infeciton
| Pathway Id | Pathway description | S gene number | TS gene number | B gene number | TB gene number | P value of Fisher’s exact test |
|---|---|---|---|---|---|---|
| 4144 | Endocytosis | 158 | 3220 | 181 | 4524 | 0.000000 |
| 4510 | Focal adhesion | 163 | 3220 | 193 | 4524 | 0.000008 |
| 4010 | MAPK signaling pathway | 209 | 3220 | 257 | 4524 | 0.000084 |
| 5410 | Hypertrophic cardiomyopathy (HCM) | 74 | 3220 | 84 | 4524 | 0.000168 |
| 4916 | Melanogenesis | 86 | 3220 | 100 | 4524 | 0.000344 |
| 4012 | ErbB signaling pathway | 73 | 3220 | 84 | 4524 | 0.000490 |
| 5214 | Glioma | 57 | 3220 | 64 | 4524 | 0.000509 |
| 5210 | Colorectal cancer | 72 | 3220 | 83 | 4524 | 0.000605 |
| 4512 | ECM-receptor interaction | 70 | 3220 | 81 | 4524 | 0.000917 |
| 4142 | Lysosome | 95 | 3220 | 113 | 4524 | 0.000946 |
| 5220 | Chronic myeloid leukemia | 63 | 3220 | 73 | 4524 | 0.001796 |
| 5223 | Non-small cell lung cancer | 47 | 3220 | 53 | 4524 | 0.002023 |
| 4910 | Insulin signaling pathway | 109 | 3220 | 133 | 4524 | 0.002627 |
| 5212 | Pancreatic cancer | 61 | 3220 | 71 | 4524 | 0.002697 |
| 4912 | GnRH signaling pathway | 78 | 3220 | 93 | 4524 | 0.003094 |
| 4722 | Neurotrophin signaling pathway | 101 | 3220 | 123 | 4524 | 0.003313 |
| 4130 | SNARE interactions in vesicular transport | 32 | 3220 | 35 | 4524 | 0.003616 |
| 4520 | Adherens junction | 62 | 3220 | 73 | 4524 | 0.004499 |
| 4514 | Cell adhesion molecules (CAMs) | 105 | 3220 | 129 | 4524 | 0.004825 |
| 5414 | Dilated cardiomyopathy | 72 | 3220 | 86 | 4524 | 0.004880 |